Checkpoints in Adenoviral Production: Cross-Contamination and E1A
نویسندگان
چکیده
منابع مشابه
Checkpoints in Adenoviral Production: Cross-Contamination and E1A
Adenoviruses are widely used for overexpressing proteins in primary mammalian cells. Incorporation of the early viral gene, E1A, or viral cross-contamination can occur during amplification, and identification of these products is crucial as the transcription of unwanted genetic material can impact cell function and compromise data interpretation. Here we report methods for evaluation of contami...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0023160